Researchers reveal translocation mechanism of pre-60S nuclear export through nuclear pore complex
Nuclear pore complex (NPC), one of the largest proteinaceous machines in eukaryotes, mediates the nucleocytoplasmic transport of macromolecules and participates in many important cellular processes. In recent years, the intricate 3D architectures and fine structures of the NPC are now being unveiled by combing cryo-EM technology, x-ray crystallography, mass spectrometry, and artificial intelligence. However, the […]
2023-06-01|Research